The main interest of the Ji lab is to elucidate the epigenetic regulation of normal cellular differentiation and chronic respiratory diseases such as childhood asthma. Specifically we are interested to understand the epigenetic mechanisms underlying heterogeneous disease phenotypes and mediating the impact of environmental exposures.
Currently, we are focused on understanding how epigenetic mechanisms regulate disease severity in childhood asthma. We are also investigating how diesel exhaust particles and other exposures modify the epigenome, leading to increased susceptibility to chronic common diseases. The approaches we have taken include human population studies, animal models and in vitro cell models.
We have open positions in our lab for both students and postdocs! Contact Hong Ji at email@example.com for more details.